Drs. Sam'l Swan, I. C. Boardman, Thomas Wildes, E. A. Ballard, Wm. Eggert, Laura Morgan, H. I. Ostrom, Wm. Bradshaw, Thomas Skinner, R. M. Theobald, S. Morrison, D. W. Clauson, C. F. Nichols, E. W. Berridge, Francis Burritt, S. W. Jackson, R. N. Foster, E. B. Nash., Julius Schmidt, C. W. Boyce, W. A. Hawley, D. B. Morrow, J. R. Haynes, H. H. Carr, H. C. Allen, J. T. Kent.
Dr. Swan's provers : Miss Eva Spalding, Miss Hays, Mrs. Mary B. Pitts, Mrs. S. S., Mr. Brown, a lady, a woman, five provers (names and sex unknown). Dr. Morrison's prover : Mrs. ---. Dr. Berridge's prover : Mrs. W. Heitts. Dr. H. B. Carr's provers : Dr.---, Mrs. Henry Hake, Mrs. Kelt. Copland's Dictionary.
Dr. Fellger said it was absurd to claim that any disease could be cured by its nosode, for after potentizing the nosode, we cannot be satisfied that it is in the same condition as when first taken from the diseased individual. Thus the syphilitic poison is composed of molecules of atoms. When the poison is potentized the essential character of the molecules is undoubtedly lost, and hence it is not the same substance any longer. Therefore, there can be no certainty that the potentized preparation is the same poison. But it, for argument, we allow that the molecules of the poison can be potentized without change of character, we still are not relieved of the dilemma, for primary syphilis in any one person will make a different set of symptoms from syphilis in another person. The variations are endless. Hence, we must then have a potentization of each one of these different kinds of syphilis, which would be impossible. Mercury is a staple substance, always unchanged ; it might then be expected to produce identical sets of symptoms on any number of the most different people. Yet its action is different upon every person to whom it is given. How much more, then, must be the individual variations in the case of the poison of syphilis, and if mercury requires so many different remedies to antidote it, how much more, then, must syphilis need a variety of remedies to treat it. It is folly, then, to expect to treat symptoms with its nosode, and the folly is the more apparent when we realize that the character of this nosode is essentially changed in the process of potentizing. The only way, therefore, to use a nosode is to prove it on the healthy like any other drug, and note its symptoms in the regular way.

Characteristics :
Pains from darkness to daylight ; begins with twilight and ends with daylight (Merc., Phyt.).
Pains increase and decrease gradually (Stan.) ; shifting and require frequent change of position.
All symptoms are worse at night (Merc.) ; from sundown to sunrise.
Eruptions : dull, red, copper-colored spots, becoming blue when getting cold.
Extreme emaciation of entire body (Abrot., Iod.).
Heart : lancinating pains from base to apex, at night (from apex to base, Med.) ; from base to clavicle, or shoulder, (Spig.).
Loss of memory : cannot remember names of books, persons or places ; arithmetical calculations difficult.
Sensations : as if going insane ; as if about to be paralysed ; of apathy and indifference.
Terrible dread of night on account of mental and physical exhaustion on awakening ; it is intolerable, death is preferable.
Fears the terrible suffering from exhaustion on awakening (Lach.).
Leucorrhea : profuse, soaking through the napkins and running down to the heels (Alum.).
Headache, neuralgic in character, causing sleeplessness and delirium at night ; commencing at 4 P. M. ; worse from 10 to 11 and ceasing at daylight (ceases at 11 or 12 P. M., Lyc.) ; falling of the hair.
Acute ophthalmia neonatorum ; lids swollen, adhere during sleep ; pain intense at night < from 2 to 5 A. M. ; pus profuse ; > by cold bathing.
Ptosis : paralysis of superior oblique ; sleepy look from drooping lids (Caust., Graph.).
Diplopia, one image seen below the other.
Teeth : decay at edge of gum and break off ; are cupped, edges serrated ; dwarfed in size, converge at their tips (Staph.).
Craving alcohol, in any form.
Hereditary tendency to alcoholism (Sar., Psor., Tuber., Sulph., Sulph. ac.).
Obstinate constipation for years ; rectum seems tied up with strictures ; when enemata were used the agony of passage was like labor (Lac. d., Tub.).
Fissures in anus and rectum (Thuja) ; prolapse of rectum ; obstinate cases with syphilitic history.
Rheumatism of the shoulder joint, or at insertion of deltoid, < from raising arm laterally (Rhus - right shoulder, Sang. left, Fer.).
When the best selected remedy fails to relieve or permanently improve in syphilitic affections.
Syphilitics, or patients who have had chancre treated by local means, and as a result have suffered from throat and skin troubles for years, are nearly always benefited by this remedy at commencement of treatment unless some other remedy is clearly indicated.
Relations : antidote ; Nux vomica, for over-action or excess of action in sensitive organizations, or too frequent repetition of the remedy, especially in the higher potencies.
Compare : Aur., Asaf., Kali iod., Mer., Phyt., Nit. ac. in diseases of bone and syphilitic affections. Ech., Lac can., Med. in dysmenorrhea. Calc., Tub., headache deep in the brain. Plat., Stan., pains increase and decrease slowly. Alum., Kali bi., Puls., Psor., Sep., Teuc., post-nasal catarrh, or ozæna, with offensive plugs or clinkers. Hepar, Sil., Psor., tendency to successive abscesses (succession of boils, Anthr.). Aur., Lac can., Lach., Mer. iod., syphilitic stomatitis. Calc. fl., Fluor. ac., Kali bi., Kali iod., Mang., Mer., syphilitic nodes. Abrot., Iod., Tub., progressive emaciation. Med., lancinating pains in heart (from apex to base). Spig. (from base to clavicle or shoulder). Syph. (from base to apex). Lach., fear of exhaustion on awakening. Caust., Gels., Graph., paralysis of upper lids. Asar., Med., Psor., Sul., Tub., hereditary tendency to alcoholism. Lac. d., Tub., paralytic weakness of rectum with labor-like pains. Nat. mur., Sanic., Thuya, fissure ani. Kreos., Mer., troubles during dentition, especially if hereditary syphilis be suspected. Phos. X-ray, bad effects of thunder-storms.

Aggravation :
Motion, touch, hot or cold things, warm or damp weather, seaside, electric storms, winter, raising arms laterally, at night (in common with all anti-syphilitics).

Amelioration :
Cold bathing, in the mountains, warmth, walking.

Mind :
Loss of memory.
Loses remembrance of passing occurrences, names, dates, etc., while all occurrences previous to inception of disease are remembered as distinctly as ever, almost without effort.
Very nervous, weeping without cause.
Cross, irritable, peevish.
Irritable, excited, walking much of the time, does not want to be soothed, violent on being opposed, has tremors, seems on the verge of convulsions, dazed, absent-minded, always washing her hands.
Periodical neuralgia in head.
Very despondent, does not think he will ever get better.
Feeling as if going insane, or about to be paralysed.
A far-away feeling, with apathy and indifference to future.
Crying infants, who begin immediately after birth.
Difficulty in making arithmetical calculations.
Terrible dread of night, not on account of cough so much as on account of mental and physical exhaustion when she awakes ; it is intolerable, death is preferable ; she fears to prepare for night and is positively in abject fear of suffering, in form of exhaustion on awakening ; it is < by cough, but it is quite independent of cough as she wakes in this awful state ; always < at night approaches ; leaves her about daylight, which she prays for.
Spring cough.
Had had a dose of Syphilinum cm., twenty-four hours before ; on third night her anxiety and cough returned, though very much less.
Another dose of Syphilinum cm., next morning, removed all symptoms, including aphonia, and exhaustion requiring brandy.
Great difficulty, and sometimes impossibility, of concentrating the thoughts on particular subject ; yet at the same time can recollect consecutive events and details which occurred 25 or 30 years previously in the order of occurrence, almost within effort.
Cannot remember names of persons, books or places.

Head :
Vertigo on looking up, seems to be caused by heat.
Headache : linear, from or near one eye backward ; lateral ; frontal ; from temple to temple ; deep into brain from vertex ; as from pressure on vertex ; in either temple, extending into or from eye > by warmth ; in bones of head ; < by heat of sun ; after sunstroke.
Sick headache, pains intolerable, arteries of head full and pulsating violently ; high fever, frequent retching on trying to vomit ; menses regular, but very scanty.
Lancinating pain in occiput, < invariably at night, and causing sleeplessness, but always ceasing with the coming light of morning.
Headache and great debility.
Neuralgic headache causing sleeplessness or delirium at night, always commencing about 4 P. M. ; < at from 10 to 11 P. M., and ceasing at daylight.
Bursting sensation in vertex as from severe cold.
Pain from eyes through to occiput, with sensation of weight in occiput drawing head back ; or as if it were pulled back ; eyes aches and smart.
Constant linear headache, commencing at both angles of forehead and extending in parallel lines backward a precursor of epileptic attack.
Heavy, crushing, cutting pain across base of cerebellum.
Heavy, clouded dull feeling in base of brain.
Headache through temples, thence vertically like an inverted letter T.
Coronal headache.
Headaches accompanied by great restlessness, sleeplessness and general nervous erethism.
Syphilitic headache for many months, piercing, pressing excruciating over right eye extending deep into brain ; losing continuity of thought and memory ; makes repeated mistakes in figures.
Suffusion and full feeling in face, throat and head, with innumerable small enlarged cervical glands.
Sore, one and a half inches in diameter, on occipital bone, covered with a thick, yellow-white scab.
Dirty eruption on scalp.
Great loss of hair.
Nervous chills preceded by aching pains in head, especially in occipital and integuments thereof, head feeling heavy, sore, congested ; also frontal headache about one-half or two-thirds inches wide across forehead under eyebrows ; aching pains below waist, in pelvis and extremities, especially in tibia, which is sensitive to touch ; pains commence about 4 P. M., culminate about midnight in delirium, and cease entirely at daylight.
Syphilitic cephalalgia in occiput, intolerable, extending to nervous ganglia of neck, causing hardening of cords ; attacks at irregular intervals, especially after excitement.
Cephalalgia in nerves of scalp, invariably worse at night and better after daybreak.

Eyes :
Red papulous eruption round left inner canthus, with isolated pimples on side of nose, cheek and eyebrow ; these pimples were red, with depressed centre, circumscribed areola, became confluent where they were most dense ; pimples bleed when scabs come off ; agglutination of lids.
Sensation of heat with a little pain in outer half of left lids.
Sharp, pulsating pain, occasionally at outer end of superior border of right orbit, apparently in periosteum.
Upper lids swollen.
Ptosis : paralytica ; eyes look sleepy from lowering of upper lid.
Diplopia, one image seen lower than the other.
Strabismus paralytica, eye turning inward, and pupil can only be turned outward as far as median line.
Chronic recurrent phlyctenular inflammation of cornea ; successive crops of phlyctenules and abrasion of epithelial layer of cornea ; intense photophobia ; profuse lachrymation ; redness and pain well marked ; delicate, scrofulous children, especially if any trace of hereditary syphilis remains.
Left eyeball covered with fungus-like growth, pain intense < at night.
Acute ophthalmia neonatorum.
Redness and swelling of outer half of both lower tarsal edges.
Syphilitic iritis, intense pain steadily increasing night after night ; < between 2 and 5 A. M., coming almost at the minute and ceasing same way.
Pain in right inner canthus as if blood went there and could go no further, also in right temple.
Both eyes glued in morning ; conjunctiva injected ; photophobia, constantly wears a shade.
Eyes dull.
Infantile syphilis.
Ophthalmic pains, < at night, > by cold water.
Right eye alone affected, congestion of conjunctiva and sclerotica, with some chemosis ; lids inflamed, esp. at outer canthus ; sensation of sand in eyes ; lids agglutinated in morning ; great photophobia (hereditary syphilis).
Neuralgia every night, beginning about 8 or 9 P. M., gradually increasing in severity until it reached its height about 3 or 4 A. M., and after continuing thus for two or three hours, gradually decreased and finally ceased about 10 A. M. ; attacks gradually get more severe and last longer ; first feels cold all over, almost a shiver ; then soreness as if beaten in right half of head, extending a little beyond middle line on vertex ; in about thirty minutes scalding lachrymation from right eye, with shooting backward therein ; eye is very red and closes, with photophobia ; gnawing pains extend down right side of face and whole of nose ; head is worst when eye is bad ; during paroxysm right eye feels as if lids were open wide, and cold air blowing on exposed eye ; she perceives a horizontal band across pupil of right eye hindering sight ; this came on soon after paroxysms commenced ; eye > by placing handkerchief on head and letting it hang over eyes, also by gentle pressure, though she cannot bear much pressure ; it is more painful when lying on right (affected) side when also right side of head feels sore ; right eye red, and red vessels run all over it, converging towards iris ; right pupil horizontally oval ; right iris looks dull and there is a slight brown hue around pupil left eye normal ; attacks seem to have originated from sitting at window in a cold draft, right eye being next window.
During sleep lids adhere ; in infantile syphilis.
Paralysis of superior oblique.
Chronic recurrent phlyctenular inflammation of cornea ; successive crops of phlyctenules and abrasion of epethelial layer of cornea ; intense photophobia ; profuse lachrymation ; redness and pain well marked ; delicate scrofulous children, especially if any trace of hereditary syphilis remains.
Interstitial keratitis.
Photophobia, black spots, shreds or veils before sight.
Itching of left inner canthus.
Eyes very red and inflamed.
Acute ophthalmia neonatorum.
Eyes swollen and closed with syphilitic ophthalmia, pus running out of them.
Acute left conjunctivitis, with considerable pain in eyeball, photophobia and lachrymation, followed by iritis ; nocturnal aching in eyeball, pain extremely violent from 2 to 5 A. M. ; sight impaired.
Iritis with photophobia, congestion of conjunctiva and sclerotica, with puffiness of conjunctival mucous membrane ; chemosis, pupil immovable, diminution of sight ; supraorbital pain.
Pain in right inner canthus as if blood went there and could go no further, also in right temple.
At 1 P. M. scalding lachrymation of right eye with shooting therein, followed by shooting from around eye into eye ; eye red and closed ; this lasted about an hour, then decreased, ceasing about 3 P. M. ; recurred for two successive days and again four days afterwards in a slighter degree, but at same hour.
On turning eye to left feels momentary coldness in inner half of right eye.
On waking, gum in right canthus.
On walking across room, right eye sensitive to air, aches on using it.
Left eye closed, upper lid swollen as large as half an English walnut ; deep red, not much pain, with oozing of purulent matter from between lids.
Strabismus paralyticus, the rectus internus being involved, and the eye turning outward.
Left eyeball covered with a fungus-like growth, pain intense, worse at night.

Ears :
Intense earache in right ear, incisive pains thrusting into ear ; purulent watery discharge from ear with pain.
Gathering in left ear which discharges a great quantity of pus (hereditary syphilis in a child).
Deafness gradually increasing until she could scarcely hear at all.
Complete deafness ; nothing abnormal to be seen.
Catarrhal or nerve deafness with marked cachexia.
Calcareous deposit on tympanum.
Small, acrid, watery discharge occasionally from ears, no deafness (ozæna).

Nose :
Left side of nose, inside ala, itching.
Nose stuffed up and burning.
Attacks of fluent coryza.
Offensive, thick yellow-green nasal discharge ; during sleep dry scabs form in both nostrils ; following an application of salve for sore eyes ; left submaxillary gland, which had been swollen and indurated softens, discharges, and, after forty-five days, begins to heal slowly.
Ozæna syphilitica.
(Syph. brought out an eruption of sores with a fiery-red base on nose over frontal sinuses).
Left side of nose inside and out very sore, likewise lips and chin ; sores itching and scabbing over ; after Syphilinum 1 m. much better in twelve hours, many drying up and scabs falling off leaving skin beneath of a dull-reddish copper color.
Itching in nostrils.

Face :
Face drawn to one side, difficulty of speaking, masticating, blowing.
Spasmodic twitching of many muscles, esp. in face (paralysis agitans), with great melancholy and depression of spirits.
Facial paralysis right side, thick speech, hemicrania, jactitation of right eye and lid.
An old gentleman has had for some years cancer on right malar bone ; no rest, his agony excruciating in extreme (relieved).
Face pale.
Itching, scabby, eczematous eruptions singly or in clusters, looking like herpes.
Nose and cheeks covered with eruptions and scabs in layers rising to a point.
Dark purple lines between alæ nasi and cheeks.
Lips and teeth covered with bloody mucus.
Sores on lips and chin, esp. left side, scabbing over.
A boy, aged 20 months, fretful, peevish, cross and crying, tossing in his sleep, grinding his teeth, face dotted with papules filled with a watery yellowish matter, most on edges of lids ; teeth irregular, arms and legs emaciated, very tottery on his feet, very nervous.
Left submaxillary gland which had been swollen and indurated, softens and discharges, and after forty-five days begins to heal slowly.

Teeth :
Single small lunæ cleft in upper incisors, permanent set, which incisors are dwarfed in their general dimensions, and converge at their tips ; inherited syphilis.
Children's teeth are cupped.
Teeth decaying at edge of gum and breaking off.
Felt like a worm in tooth, could not tell which tooth.
Singular feeling as if teeth had all got out of place, and on closing jaws teeth do not come well together.
First central upper incisors serrated, permanent teeth point towards each other, inner side concave ; edges serrated.
Pain in right upper jaw, as if from teeth, with swelling of face.
Painless fluttering occasionally in teeth, very peculiar, as if something alive, cannot detect which tooth it is.

Mouth :
Tongue red and thick ; two deep cracks running lengthwise in it ; one on each side of median line.
Aphasia, difficulty of finding words ; debility.
Tongue feels as if paralysed.
Fetid breath.
Tongue coated white, edges indented by teeth.
Tongue turns to one side when protruded ; difficulty in mastication, cannot turn food with tongue so readily from right to left as in other direction.
Putrid taste in mouth before epileptic fit.
Tongue very red and thick ; covered with herpetic eruption, two deep cracks running lengthwise on each side of median line, making it difficult to swallow.
Tongue thickly coated, dirty, edges indented or serrated by teeth.
Twenty ulcers in mouth, every part involved, top and under side of tongue, lips, buccal cavity, fauces and nose.
Two large ulcers, one on each side near apex of tongue, were very much swollen, and the one on right side had a gangrenous center, the rest lardaceous bottoms with bright fiery red edges, and were cut down as with a knife, and left hard like an indurated chancre.
Septum of nose threatened, both alæ nasi very painful, smarting with burning as if on fire ; pains and burning prevented sleep ; hungry but could eat nothing but fluids, as mastication was impossible ; tongue heavily coated white, large quantities of stringy, viscid saliva running from mouth, of a sweetish taste ; a putrid sickening odor filled whole house ; all symptoms < toward night.
This attack excited by exposure to rain.
Herpetic eruption in mouth, tonsils, hard palate and fauces, completely covering inside of mouth and throat, making it difficult to swallow even liquids.
Syphilitic destruction of hard and soft palates.
Chancre on hard palate exposing the bones of roof of mouth.

Throat :
Chronic hypertrophy of tonsils.
Chancrous ulcer extending across velum palati to left pillar of pharynx, which was congested and thickened, interfering very much with his speech ; voice husky.
Acute pharyngitis.
Sore throat.
Deglutition painful, especially with liquids.
Excoriation of throat when swallowing.
Sore throat with granulations.
Chancrous ulcers in pharynx.
Herpetic eruption in mouth, tonsils, hard palate and fauces, completely covering inside of mouth and throat, making it very difficult to swallow even liquids.

Appetite :
Appetite indifferent and capricious.
Total loss of appetite for months, little or nothing satisfies him ; formerly was generally ravenous.
Loss of appetite.
Appetite good again ; ravenous desire for food even after a meal.
Tendency to heavy drinking ; alcoholism.
Aversion to meat.
Dyspepsia ; flatulence, belching of wind ; nervous dyspepsia.

Stomach :
Heartburn with pain and rawness from stomach to throat pit, often with cough.
Vomiting for weeks or months due to erosion from superficial ulceration of lining of viscus, herpetic, of syphilitic origin.

Abdomen :
Pain or distress deep in abdomen as if in omentum.
Feeling of heat internally in hypogastric region.
Pain in right groin followed by swelling of glands.
Large painless bubo in right groin opened and discharged freely.
Slight lancinating pain in one groin, < at night.
Inguinal bubo.

Stool and Anus :
Bowels torpid for five weeks.
Obstinate constipation for many years ; rectum seemed tied up with stricture, when injections were given agony of passage was like child-bearing.
Chronic constipation, with fetid breath, earthy complexion, gaunt appearance.
Stools very dark and offensive.
Stools too light-colored.
Bilious diarrhea at seashore, painless, driving her out of bed about 5 A. M. ; stools during day ; later causing excoriation ; face red, suffers from heat ; occasional painless, whitish diarrhea when at home, > always by going to mountains.
Obstinate cases of cholera infantum.
Fissures in anus and rectum.
Two indurated ulcers at mouth of anus somewhat sore ; slight itching of anus.
Lower portion of rectum hanging out like a ruffle, looking like a full-blown rose fully three inches in diameter, and sensitive ; constant weak dragging sensation in rectum, extending as far as sacrum.

Urinary Organs :
Itching in orifice of urethra.
A sensation, in morning on going to urinate, as if male urethra were stuffed up or clogged, about an inch from orifice.
Scalding urine.
Urination difficult and very slow ; no pain, but a want of power, so that he has to strain.
Urine infrequent, not oftener than once in twenty-four hours, scanty, of a golden-yellow color ; after Syphilinum, woke next morning with great distention of abdomen and pain in region of kidneys ; rising she passed a large quantity of normal colored urine, after which the distention and pain were relieved ; next day regular urination, watery.
Profuse urination after chill ; passed during night nearly a chamberful.
Rich lemon-yellow scanty urine.
Frequent urging to urinate all night, at least from 7 P. M. until 5 A. M., or sunset to sunrise.

Male Sexual Organs :
Chancre on prepuce.
Burning in chancre ; ulcer size of a split pea, on prepuce above corona glands ; edges raised, bottom covered with lardaceous deposit ; no pain or sensation in it.
Glans purple, on left side covered by an exudation.
Chancre on penis, third in two years, all on same spot.
Aching of genitals, could not sit still for over a month.
After suppressed chancre, disease attacked testes, and scrotum, which became painful and swollen ; this was supposed to be cured, but ever since, every few weeks, if exposed to damp weather would be seized with pain as if in kidneys, seemingly traversing ureters, but instead of passing into bladder followed spermatic cord, down groins and into testes ; pain agonizing, chiefly in cord, in present attack in right ; pricking in chancre, as though punctured by pins.
Chancroid, phagedenic, spreading rapidly ; buboes commencing in each groin.
Inflammation and induration of spermatic cord.
Constant pain in anterior part of right thigh, < while standing, painful all night, preventing sleep ; bubo in left inguinal region size of a pigeon's egg, purple, fluctuating ; night sweats.
Bubo, purple, pointing in left groin, size of pigeon's egg ; accompanied with night sweats, and constant pain in anterior portion of right thigh, < at night.

Female Sexual Organs :
Uterine and all surrounding parts loose, soft and flabby ; profuse, thick, yellow leucorrhea ; constant pain across small of back.
Slight whitish leucorrhea.
Yellow offensive leucorrhea, watery or not, so profuse it daily soaks through napkins and runs to heels of stockings if much on her feet.
Profuse yellow leucorrhea < at night ; in sickly, nervous children.
Soreness of genitals, and muco-purulent discharge, in a child.
Acrid discharge causing violent itching and inflammation of external organs < at night from warmth of bed, parts very tender ; itching and inflammation > during menses.
Nocturnal < of right ovarian pain, preventing sleep.
Sore on right labium majus, extending to left
Intense itching of vulva on rising in morning, continuing until 10 o'clock.
Menstruation painful, two weeks too soon ; pink-red, bright, profuse, running free for some days ; napkins wash easily.
Menses returned in 28 days, painless.
Painful menstruation.
The usually painful menstruation with all its concomitants, was very easy and the best for years.
Sensitiveness of os uteri, < to intolerable pain at menses, or on introduction of finger or penis ; frequently causes abortion.
Sharp zigzag shooting pains in region of uterus.
Ovaries congested and inflamed ; tendency to ovarian tumors.
Sore aching in left ovarian region, extending to right with darting pains.
Left Ovary swollen, during coitus, at moment of organism, a sharp cutting pain like a knife, and twice there was smarting as of a sore ; ovary swelled so much that its size and shape could easily be felt through abdominal walls (caused by Buboin).
Uterine and ovarian diseases with pronounced nervous disorders, esp. in married women.
Mamma sensitive to touch, feeling sore, during menses, and at other times.

Respiratory Organs :
Hoarse, almost complete aphonia, day before menses.
Diseased cartilages of larynx.
Pain and oppression at bifurcation of bronchia and in larynx, it hurts her to breathe.
Attacks of spasmodic bronchial asthma for twenty-five years ; they come on only at night after lying down or during a thunderstorm, producing most intense nervous insomnia, entirely preventing sleep for days and nights.
Violent attacks of dyspnŇďa, wheezing and rattling of mucus, from 1 to 4 A. M.

Cough :
Hard cough < at night, when it is continuous preventing sleep.
Hard, constant cough with thick, yellow, tasteless expectoration.
Dry, racking cough, with thick, purulent expectoration, caused by a sensation of rasping or scraping in throat, always < at night.
Whooping-cough with terrible vomiting.
Cannot lie on right side, as it causes a dry cough.
Muco-purulent expectoration, greyish, greenish, greenish-yellow, tasteless.
Expectoration without cough, quite clear, white, feels like a round ball and rushes into mouth.
Cough and dyspnŇďa come on after midday dinner, has to fight for breath, feels as if she would be suffocated¬†; symptoms last all night, > at daybreak (improved).
Expectoration of white phlegm.
Dry, sharp, hacking cough without expectoration, but with rawness, scraping and burning from fauces to stomach pit ; with a whoop in inspiration and a choking sensation from fauces to bifurcation of bronchia, great mental distress.
Hard cough, < at night, when it is continuous, preventing sleep ; white phlegm expectorated.
Cough < on lying on right side.
Hoarse, almost complete aphonia, the day before menses ; no catarrh or sore throat.

Chest :
Chronic asthma ; in Summer, especially when weather was warm and damp ; most frequently in evening, passing off at daybreak ; soreness of chest, with great anguish and inability to retain a recumbent position ; in Winter severe bronchial cough succeeded by asthmatic attacks ; a regular type of chills and fever developed ; suffered from this many years before.
Within 24 hours after taking the character of the asthma changed, during the night it disappeared, and the hour which had been that of relief, now became that of aggravation.
The attacks only lasted a few minutes, and gradually becoming less severe, did not return for several months.
Oppression of chest to such an extent as to almost arrest breathing ; asthma caused by sensation as if sternum were being gradually drawn towards dorsal vertebra ; expansion of chest difficult ; confusion of mind, as if unconsciousness might follow.
Attack lasted about ten minutes, followed by general weariness which passed off in a few hours.
Rattling in chest and throat.
Pain in centre of chest as if skin were drawn up, on drawing the head back.
Lack of sleep produces sudden faintness and sinking sensation in chest ; three spells succeeded each other during a single night.
Sensation of pressure under upper part of sternum.
Pain and pressure behind sternum.
Angina ; ptosis left eye ; facial paralysis left side, slight aphasia ; impotence (relieved).
Eczematous herpetic eruptions on chest.
A lady, 78 years of age, had suffered from attacks of spasmodic bronchial asthma for 25 years. The attack would come on only at night after lying down, or during a thunder-storm, and produces the most intense insomnia, entirely preventing sleep for days and nights together. Under allopathic treatment full doses of Morphine brought relief for twenty months.
Ars., Amb., Bell., Ipecac, Nux, Phos., Sul., Op. high and other apparently well selected remedies entirely failed. Syphilinum cm. cured.

Heart :
Lancinating pain in heart at night, from base to apex (Medor. has reverse).
Valvular disease of the heart.

Neck and Back :

Heavy aching and stiffness from base of neck up through muscles and cords into brain.
Great pain in back in region of kidneys, < after urinating.
Pain in coccyx at its junction with sacrum, sometimes in lower sacral vertebræ ; < on sitting, with a sensation as if swollen, though it is not.
Pains commencing in sacral regions internally, and apparently coming around to uterus.
Caries of cervical spine with great curvature in same region, directly forward, occiput sinking down to a level with it and resting on protuberance of curvature ; often nearly a teaspoonful of calcareous matter would be discharged at a time and on evaporating it a quantity of dry powder, looking like phosphate of lime, would be left ; pain in curvature always < at night (no proof of syphilis).
Rigidity of muscles.
A heavy, dragging, dull feeling in lumbar region, with stiffness and want of elasticity.
Caries or dorsal vertebræ with acute curvature, numerous cloacæ communicating with diseased bone, one much larger than the rest, exuding a sanious, offensive pus, and surrounded with proud flesh ; great thickening and induration of surrounding parts from effusion of lymph ; percussion or pressure not endurable ; two abscesses in groins, left having been opened a year before right about a month ago ; least motion gave him great pain by day ; and terrific pain by night ; for five months, every night most intense neuralgic pains, commencing generally from 5 to 7 P. M. and never terminating till about daylight or about 5 A. M. ; pains in muscles of loins, generally in left, sharp, cutting spasms, terrible to bear, preventing sleep and forcing him to cry out ; < at least motion, and slightly > by warm poultices.
Psoas abscess first left then right latter discharged more than a quart of offensive greenish pus when opened ; severe nocturnal pains, affecting upper sacral, lower dorsal and left cervicofacial regions, steadily increasing ; they occurred twice, each time twenty-one days after either psoas abscess had been opened.
Enlargement of cervical glands and a number of pedunculated pin-head warts on neck ; cured by syco-syphilinum.
Enlargement of glands in different parts of the body, particularly abundant about the neck ; indurated and slightly painful causing a sensation of uncomfortable fullness and suffusion in face, throat and head.
Nocturnal aggravation of pains in back, hips and thighs.
Enormous swelling of glands in head neck ; no relief from any remedy.
Cured with Buboin syphilitica cm.
Syphilitic sores on back near spine on hip.
Pains commencing in sacral region internally, and apparently coming around to uterus.
Indurated lumps between muscles of the neck.
Aching pains in limbs like growing pains.

Upper Limbs :
Rheumatism of shoulder-joint or at insertion of deltoid, < from raising arm laterally.
Can only raise arms to a right angle with axilla ; trying to force them higher causes muscles to suddenly become paralysed and they drop pendant.
Lameness and pain of arm on motion < on raising arm up in front as if reaching ; pain located about insertion deltoid in upper third of humerus, not painful to pressure.
Fingers and thumbs have runarounds (infantile syphilis).
Always washing the hands.
Hands badly ulcerated on backs.
Right second finger is swollen and stiffened.

Lower Limbs :
Swelling of legs from knees down, soles painful when standing on them ; swelling goes down in morning, comes back at night.
Pains in lower extremities, excruciating, completely banish sleep ; < from hot fomentations ; > pouring cold water on them > for an hour, after which the pains returned.
Cannot sit in a low chair, or squat down, owing to loss of control over knee and hip-joints.
Pains in long bones of lower extremities, also on joints.
Dull pains over back of feet to toes, began soon after getting into bed, lasting until 4 or 5 A. M.
For two or three winters intense cold pain in both legs, < in left, came on every night on lying down, lasting all night ; > by getting up and walking, and in warm weather.
Pain in three toes of right foot as if disjointed.
Slight contraction of tendons beneath right knee.
Tearing pains in hip and thighs, < at night > about daybreak, < by walking, not affected by weather (improved).
Redness and rawness with terrible itching between toes.
Bubo with pain in spot on middle of right thigh in front, only when standing and on deep pressure, which seemed to touch spot, which was apparently on periosteum.
Two ulcers larger than a crown piece, dirty stinking, sloughing, with jagged, elevated edges, one on thigh above patella, another on head of tibia ; two large pieces of bone came away from head of tibia.
Osteosarcoma in centre of right tibia the size of half an ostrich egg, pains agonizing at night, growth irregular, spongy, partly laminated, very hard.
Contracted, painful feeling in soles, as if tendons were too short.
Aching pains in limbs, like growing pains.
Bone pains in knees and feet.
Gradual rigidity of all joints after eruption ; flexors seem contracted.
Rheumatic swelling of left wrist and big toe, bluish-red, with pains as if somebody sawed at his bones with a dull saw ; > by heat of stove ; < from sundown to sunrise ; no appetite ; has lasted two weeks.
Feeling of numbness in palms and soles, at times a prickly sensation as if numb parts were punctured by a great number of needles.
Excruciating arthritis ; swelling, heat, and redness intense.
Rheumatism, muscles are caked in hard knots or lumps.
Severe attacks of aching in lower limbs.
Sharp rheumatic pain, burning like fire, in left side of right instep and below inner malleolus, prevents her from moving foot < when toe is pointed inward ; < in evening, continuing during night, waking her up suddenly every two or three hours, worst from 1:30 to 3:30 A. M., < toward daybreak (improved).
An old doctor residing here had been troubled for two or three winters with an intense cold pain in both legs, left one worse.
It came on every night on lying down and lasted all night, only relief was by getting up and walking, and everything had failed to help.
Magnetic leggings had afforded most relief.
The trouble ceased in warm weather.
He happened to speak of it one day, and I told him when it returned in a milder form, and he received one dose of Syphilinum cmm., and he has never had it since.
Went all winter without pain.
But he said the second powder made his genitals ache so that he couldn't sit still, and this continued for over a month.

Skin :
Pustular eruption on different parts of body ; in patches on certain places, particularly on wrists and shins, where bones are nearest cuticle, and isolated other large pustules on other parts, these break, discharging an ichorous fluid for one or two days, then heal, leaving characteristic pockmark cicatrice ; patches take longer to heal, discharging same fluid till healing process commences.
After healing of chancre a fresh pustular eruption appears on different parts of body, which when pustules have discharged an ichorous liquid and healed up, leaves fresh coppery pockmarks ; Medorr. removed it permanently, causing it to turn yellow-brown, dry at edges and scales off, leaving skin permanently clear and free.
Biting sensation in different parts of body, as if bitten by bugs, at night only.
Syphilitic rash, very prominent on forehead, chin, arms and front of thorax, an abundance of fine scales peeling off ; large prominent spot on centre of forehead, filled with fluid, as also are some smaller patches.
Syphilitic bulla discharging freely on cheeks, under chin, on back of shoulders, on scalp and other parts of body (infantile syphilis).
Macula : copper-colored ; from crown of head to sole of foot.
Pemphigus, looking like a pock, often confluent and persistently reappears.
Skin bluish.
Macula over back, chest, abdomen, arms and legs, but not on any uncovered part of body.
Several elevated spots on arm, stomach, leg and finger ; has them habitually on face, chiefly on left cheek.
A blood-boil on arm ; face broken out with a lumpy fiery rash.
Eruption over whole body not elevated, but could be distinctly felt by passing hand over skin ; after Syphilinum eruption came rapidly to surface ; at same time a disagreeable odor began to be developed ; eruption reddish-brown like small-pox pustules, without central depression ; body covered with it, except scrotum and penis ; increased, completely covering inside of mouth and throat, making it difficult to swallow even liquids ; eyes also covered, making him completely blind ; intolerable smell from body ; tips of pimples became filled with pus ; < from warmth of bed ; fetid breath ; eruption developed still more, a great quantity of pus, with intolerable itching, yet could not scratch as it was extremely sore ; eruption left skin of entire body covered with dull, reddish, copper-colored spots, which in cold, looked blue.

Sleep :
Great restlessness at night, impossible to keep long in one position.
Absolute sleeplessness (vies with Sul. in producing quiet, refreshing sleep).
Wakes soon after midnight and cannot sleep again till 6 A. M.
During the whole 24 hours can only rest from 8 to 10 A. M.
Total loss of sleep for 22 successive days and nights.

Fever :
Great pains in head, whole body extremely cold, looked blue ; wanted to be covered with blankets or couldn't get warm ; no appetite ; sleeping almost continually, could not be aroused.
Nervous chills preceded by pains in head, esp. occiput and scalp of that part ; pains below waist, in pelvis, legs, esp. tibia, which is sensitive to touch ; bowels torpid ; cross, irritable, peevish ; pains begin every day at 4 P. M., culminate at midnight, disappear at daylight.
After retiring nerve chill beginning in anus, running down legs with spasmodic sensation ; desire for stool ; > by profuse urination and by eructations.
Fever : dry, hot, shortly after going to bed, parched lips, great thirst ; during fever intensely hot, wants to throw off covering, puts feet out of bed and against wall to cool them ; high fever in middle of day, heat being intense, with sensation as if burning up, thirst for large quantities often, sensation of burning internal heat very marked ; fever preceded by slight chill and followed by sweat and great debility.
Sweat : profuse at night, sleepless and restless ; esp. between scapulæ and down to waist, with excessive general debility.
Fever from 11 to 1 P. M. daily ; perspires when she begins to get over fever ; pain in back, < between shoulders, no ambition or desire to move.
Excessive general debility and continued night sweats, latter being most marked between scapulæ and down to waist.

Generalities :
Utter prostration and debility in morning.
Dwarfed, shriveled-up, old-looking babies and children.
Epileptic convulsions after menses.
Body, extremities and face covered with syphilides ; a sticking soreness begins in throat every evening between 6 and 7 o'clock and continues to grow < during night ; exceedingly restless until 4 P. M. ; then a restless sleep for a few hours ; can scarcely swallow ; when throbbing in throat, < from cold and hot drinks, and < lying down ; throbbing in temples and ears, boring in ears meeting in centre of brain ; sensation as if top of head were coming off ; drawing pain in eyes < from lamplight ; teeth pain when eating, also when taking anything hot or cold, feel as if they were loose, > pressing teeth together and pressing throat with hands ; excessive flow of saliva, it runs out of mouth when sleeping, severe pain in neck ; bending back head, > pain in neck ; aching pain in shoulders and knees ; rending, tearing pains throughout body, > moving about slowly ; had his wife hide his revolver lest in a fit of desperation he might kill himself, as was his desire during extreme paroxysms of pain ; strikes wall with fist and beats head against wall for relief ; stools hard, dry like sheep dung ; desire for stool three or four times a day, but only a little scentless wind passes which gives relief ; sitting at stool, > pain in head ; is easily offended, gets desperate, cannot bear to be alone, great anxiety about getting well ; at night no position suits him, walks floor or goes into street and moves about slowly ; sleepy all the time but cannot sleep ; dreams about his disease ; < in open air ; frequent urination with sudden desire ; discharges large quantities of muddy urine.
Shifting pains of a rheumatic character obliging a repeated change of position and posture.
Lancinating rheumatic pains, slightly relieved by a change of position at times, and sometimes relieved by motion.
Pains commence at 2 P. M., gradually increasing till they reach their acme at 9 P. M., continuing exceedingly acute till 3 or 4 A. M., subsiding with daybreak.
Pains more particularly < in, or confined to, the muscles and joints of lower limbs, for four or five weeks, then they seemed to go to the periosteum and bone itself, consequently becoming deeper and more profound.
The pains produce two sensations, an external one which seems to lie in muscles and joints, and an internal one which is deeper and much more unbearable, so much so that it seems by its profound nature to control the external ones and to cause those pains to disappear, afterward reappearing intensified in the external sensation.
Pains in all the limbs every night after midnight, weary, tired pains, making rest impossible, as he could lie nowhere without suffering in the part on which he rested.
Pains worse in lower limbs, much perspiration which partly >.
Rheumatic neuralgic pains in all the muscles, even in cremaster, not in joints ; darting pains in irregular attacks, sometimes lasting a week or two.
The pains gradually increase and decrease ; they are worse in damp and especially in frosty weather ; they get worse at 4 or 5 P. M., attain their height at 2 or 3 A. M., ceasing about 8 A. M.
Never contracted syphilis very much improved by dm.
Rheumatism with sweating of hands, wrists and legs below the knees, and feet, with great soreness of soles, all < at night.
Extreme emaciation.
Hardly able to lift hand.
Feels < mornings utter prostration and debility in morning.
Weak, emaciated.
Though 17 looked 12, was so reduced and dwarfed ; great attenuation of soft parts throughout, spare and hollow ; confined to couch for about three years, and for one year was scarcely ever off back.
After the disappearance of the pustular eruption, a gradual rigidity of all the joints ensues, and all the flexors seem to become contracted and shortened ; this causes inability to close the fingers on a knife, fork or spoon, and a partial inability to lift the foot in order to step up-stairs, except with great difficulty by using a cane, and only a step up or down at a time. (Note. This is not the case where the pustular eruption is a curative effect of the Syphilinum high. - Swan).
Feeling of numbness in palms and sole, which have also at times a prickly sensation as if the numb were punctured by a great number of needles.
Slight rigidity of joints.
Rheumatic swelling of left wrist and left great toe which is bluish-red, with pains like sawing off his bones with a dull saw ; better from heat of stove, worse from sundown, to sunrise ; no appetite.